Annexin is a common name for a group of cellular proteins. They are mostly found in eukaryotic organisms (animals, plants and fungi). In humans, the annexins are found inside the cell. However some annexins (Annexin A1, Annexin A2, and Annexin A5) can be secreted from the cytoplasm to outside cellular environments, such as blood.

Feb 21, 2024 · Recent discoveries highlight annexins as sensors and regulators of cellular and organismal stress, controlling inflammatory reactions in mammals, environmental stress in plants, and cellular...

Annexin V staining is a common method used for identifying and analyzing apoptotic cells, providing valuable insights into the underlaying mechanisms of programmed cell death.

May 4, 2004 · Annexins are traditionally thought of as calcium-dependent phospholipid-binding proteins, but recent work suggests a more complex set of functions. More than a thousand proteins of the annexin superfamily have been identified in major eukaryotic ...

Annexins are an extensive superfamily of structurally related calcium- and phospholipid-binding proteins, largely conserved and widely distributed among species. Twelve human annexins have been identified, referred to as Annexin A1-13 (A12 remains ...

Annexins are Ca2+ and phospholipid binding proteins forming an evolutionary conserved multigene family with members of the family being expressed throughout animal and plant kingdoms.

Feb 21, 2024 · Annexins are cytosolic proteins with conserved three-dimensional structures that bind acidic phospholipids in cellular membranes at elevated Ca²⁺ levels. Through this they act as Ca²⁺-regulated membrane binding modules that organize membrane lipids, facilitating cellular membra …

The Annexin Homepage is dedicated to the research into the structure and function of the Annexin proteins. The site aims to enable interactions between researchers interested in this area, as well as to provide information on select aspects.

Jun 1, 2005 · Annexins are a multigene family of Ca 2+ -regulated proteins that are characterized by a unique Ca 2+ - and membrane-binding module — the annexin core domain. This core domain enables Ca 2+...

Annexins are a multigene family of Ca2+ -, phospholipid- and cytoskeleton-binding proteins with representatives in animals, plants and fungi [83–86]. They may exist in a soluble or membrane-bound state and, in plant cells, they may contribute up to 0.1% of the total protein.