
CD36 - Wikipedia
CD36 (cluster of differentiation 36), also known as platelet glycoprotein 4, fatty acid translocase (FAT), scavenger receptor class B member 3 (SCARB3), and glycoproteins 88 (GP88), IIIb (GPIIIB), or IV (GPIV) is a protein that in humans is encoded by the CD36 gene.
CD36, a signaling receptor and fatty acid transporter that …
CD36 is a type 2 cell surface scavenger receptor widely expressed in many immune and non-immune cells. It functions as both a signaling receptor responding to DAMPs and PAMPs, as well as a long chain free fatty acid transporter.
CD36, a Scavenger Receptor Involved in Immunity, Metabolism ...
CD36 is a membrane glycoprotein present on platelets, mononuclear phagocytes, adipocytes, hepatocytes, myocytes, and some epithelia. On microvascular endothelial cells, CD36 is a receptor for thrombospondin-1 and related proteins and functions as a ...
CD36 Gene - GeneCards | CD36 Protein | CD36 Antibody
Dec 24, 2024 · CD36 (CD36 Molecule (CD36 Blood Group)) is a Protein Coding gene. Diseases associated with CD36 include Platelet Glycoprotein Iv Deficiency and Coronary Heart Disease 7. Among its related pathways are Toll Like Receptor 7/8 (TLR7/8) Cascade and Epigenetic regulation by WDR5-containing histone modifying complexes.
Structure-Function of CD36 and Importance of Fatty Acid Signal ...
CD36 is a scavenger receptor that functions in high affinity tissue uptake of long chain fatty acids (FA) and contributes under excessive fat supply to lipid accumulation and metabolic dysfunction. This review describes recent evidence regarding the ...
CD36 - an overview | ScienceDirect Topics
CD36 is a class B scavenger receptor that binds various ligands such as AGE, oxLDL, fatty acids, collagen, thrombospondin, and anionic phospholipids. It is highly expressed in macrophages and macrophage-derived foam cells in atherosclerotic plaques.
CD36, a Scavenger Receptor Involved in Immunity, Metabolism
CD36 is a membrane glycoprotein present on platelets, mononuclear phagocytes, adipocytes, hepatocytes, myocytes, and some epithelia. On microvascular endothelial cells, CD36 is a receptor for throm...
CD36 facilitates fatty acid uptake by dynamic palmitoylation
Sep 21, 2020 · Restricting CD36 at either palmitoylated or depalmitoylated state eliminates its FA uptake activity, indicating an essential role of dynamic palmitoylation of CD36.
CD36-mediated metabolic adaptation supports regulatory T cell ... - PubMed
We found that CD36 was selectively upregulated in intrautumoral T reg cells as a central metabolic modulator. CD36 fine-tuned mitochondrial fitness via peroxisome proliferator-activated receptor-β signaling, programming T reg cells to adapt to a lactic acid-enriched TME.
CD36: an emerging therapeutic target for cancer and its molecular ...
CD36, a membrane glycoprotein presenting on the surface of cells, binds fatty acids to facilitate their transport for lipid utilization. Upregulated CD36 expression has been observed in multiple cancer types including acute myeloid leukemia, breast cancer, colorectal cancer, gastric cancer, etc.