Hep 3B2.1-7 [Hep 3B, Hep-3B, Hep3B] is a cell line exhibiting epithelial morphology that was isolated from liver tissue derived from an 8-year-old, Black youth with liver cancer. This cell line contains an integrated hepatitis B virus genome.

HEP3B is an immortalized human-derived hepatocyte carcinoma cell line. It is widely used in hepatotoxicity and drug metabolism research. HEP3B transfection efficiency is substantial; therefore, these cells are commonly employed to study liver cancer development, progression, and therapeutic interventions.

As cellular models for in vitro liver cancer and toxicity studies, HepG2 and Hep3B are the two most frequently used liver cancer cell lines. Because of their similarities they are often treated as the same in experimental studies. However, there are many differences that have been largely over-sighted or ignored between them.

High molecular weight genomic DNA isolated from the Hep 3B2.1-7; human; hepatocellular carcinoma cell line.

Derived from an 8 year old male. Cells contain integrated Hepatitis B virus genome. However there is currently no evidence that this cell line produces infectious Hepatitis B virus. The cells should be handled under laboratory containment level 2. Ethnicity: Black.

the cell line contains parts of the hepatitis B virus (HBV) genome integrated into the eukaryotic genome. The HBV surface antigen (HBsAg) is expressed, but no active viruses are produced by the cells. The cells can thus be handled under biosafety level 1.

The Hep3B epithelial cell line is isolated from the liver tissue of an 8-year-old Black male patient with hepatocellular carcinoma. Hep-3B cells are tumorigenic in nude mice and contain Hepatitis B. Also, the Hep-3B cell line has the Hep B virus integrated into its genome.

Sep 1, 2022 · In this manuscript we present studies that focus on the resveratrol and berberine impact on the Hep-G2 (p53 wild type) and Hep-3B (p53 null mutant) cell lines, our aim was to investigate the pro-apoptotic potential upon p53 regulated pathways.

Hep 3B2.1-7 [Hep 3B, Hep-3B, Hep3B] is a cell line exhibiting epithelial morphology that was isolated from liver tissue derived from an 8-year-old, Black youth with liver cancer. This cell line contains an integrated hepatitis B virus genome.

Cell line name HEP-3B : Species Homo sapiens (human) Cell type hepatocellular carcinoma : Incubation medium 90% MEM (with Earle's salts) + 10% h.i. FBS + 2 mM L-glutamine : Morphology epithelial-like cells growing as monolayers Tumour type -