May 6, 2024 · Detailed Tucatinib dosage information for adults. Includes dosages for Breast Cancer and Colorectal Cancer; plus renal, liver and dialysis adjustments. Skip to main content

3 DOSAGE FORMS AND STRENGTHS. Tablets: • 50 mg: round, yellow, film-coated, debossed with “TUC” on one side and “50” on the other side. • 150 mg: oval-shaped, yellow, film-coated, debossed with “TUC” on one side and “150” on the other side.

Apr 4, 2023 · The recommended dosage of tucatinib is 300 mg taken orally twice daily with or without food. For patients with severe hepatic impairment, the recommended dosage is 200 mg orally twice daily. See full prescribing information for additional information about tucatinib dosing.

For patients with severe hepatic impairment (Child-Pugh C), the recommended starting dose of TUKYSA is 200 mg orally, twice daily; Avoid concomitant use of strong CYP2C8 inhibitors with TUKYSA. If concomitant use with a strong CYP2C8 inhibitor cannot be avoided, reduce the recommended dosage to 100 mg orally, twice daily.

Mar 1, 2025 · For oral dosage form (tablets): For treatment of advanced or metastatic breast cancer with trastuzumab and capecitabine: Adults—300 milligrams (mg) 2 times a day. Your doctor may adjust your dose as needed and tolerated. Children—Use and dose must be determined by your doctor.

The recommended dosage of TUKYSA is 300 mg taken orally twice daily in combination with trastuzumab and capecitabine until disease progression or unacceptable toxicity [see Clinical...

Feb 3, 2023 · Patients received TUKYSA 300 mg orally twice per day with a loading dose of trastuzumab or a non-US approved trastuzumab product 8 mg/kg intravenously on Day 1 of Cycle 1, followed by a maintenance dose of trastuzumab …

Indicated in combination with trastuzumab and capecitabine for treatment of advanced unresectable or metastatic human epidermal growth factor (HER2)-positive breast cancer (including brain...

Jan 14, 2025 · Usual Adult Dose for Colorectal Cancer: 300 mg orally 2 times a day combination with trastuzumab until disease progression or unacceptable toxicity

Take this medication by mouth with or without food as directed by your doctor, usually twice daily (about 12 hours apart). Swallow the medication whole. Do not chew, crush, or split the...