Using artificial intelligence, researchers show how γ-secretase recognizes substrates - an important advance for fundamental and translational research. The γ-secretase enzyme is capable of cleaving ...

Metabolism: Light shed on structure of huge enzyme complex Date: February 10, 2021 Source: Martin-Luther-Universität Halle-Wittenberg Summary: A new method has enabled the natural structure of ...

The serine proteinase plasmin is the key fibrinolytic enzyme that dissolves blood clots and also promotes cell migration and tissue remodeling. Here, we report the 2.65 Å crystal structure of a ...

Scientists crack structure of enzyme complex linked to cancer. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2018 / 02 / 180207140404.htm ...

Enzyme-catalysed reactions require the specific interaction between the enzyme and its substrate in the Michaelis complex. Due to turnover, Michaelis complexes are typically transient making them ...

This enzyme builds complex sugar trees that are subsequently attached to other membrane proteins. The findings could accelerate the development of new, protein- based medications.

The cytochrome (cyt) bc1 complex is an integral component of the respiratory electron transfer chain sustaining the energy needs of organisms ranging from humans to bacteria. Due to its ubiquitous ...

10.02.2021 09:43 Metabolism: Researchers first to shed light on structure of huge enzyme complex Ronja Münch Pressestelle Martin-Luther-Universität Halle-Wittenberg. A new method has enabled the ...