As previously mentioned, the location at which a DNA strand begins to unwind into two separate single strands is known as the origin of replication.As shown in Figure 1, when the double helix ...

When organisms encounter problems—what scientists call "replication stress"—this process is more prone to errors, ... a type ...

DNA replication was identified in the late 1950s, but since then researchers across the globe have come up short trying to understand exactly how this process was regulated. Now they know.

To get there, many other steps of DNA replication still need to be understood, such as how the melted DNA origin is opened up even more fully to produce the Y-shaped DNA replication fork. “The DNA ...

The process, the researchers report in their study, published in Cell, is much more random than previously suspected. The three enzymes—helicase, primase and polymerase—are also not alwys in sync.

Scientists have determined at atomic resolution the structure of machinery that drives the process. ... How double-stranded DNA separates into single strands to start the replication process.

By uncovering precisely how G4s can block replication, scientists can now use that understanding to inform future studies and develop treatments that involve this critical cellular process. “If these ...

In the world of viral research, uncovering a virus’s weaknesses is often a painstaking process that requires years of ...

This separated the RNA double-helix—the structure that makes replication so difficult ... how those ancient RNA first began replication, a process that’s essential to understanding the foundation of ...

Genome stability depends, to a great extent, on the accuracy of the DNA replication process. ... Study details ringed structure of ORC in DNA replication. Feb 21, 2017.