The study of DNMT3A structure with substrates has long been hindered by the difficulty in producing a stable enzyme-substrate complex. "To overcome this challenge, we successfully developed a ...

Visualization of sulfite reductase's structure offers insights into sulfur chemistry, aiding in drug development and ...

Metabolism: Light shed on structure of huge enzyme complex Date: February 10, 2021 Source: Martin-Luther-Universität Halle-Wittenberg Summary: A new method has enabled the natural structure of ...

Figure 5: Standard view from the μPl substrate towards the active site of the μPl enzyme in complex with SAK (shown as a solid surface). The overall structure of the cleaved μPl substrate is ...

assuming that the interaction between enzyme and substrate is independent of the cofactors oxidation state. Here, we investigate the Michaelis complex of the flavoenzyme xenobiotic reductase A ...

The study of DNMT3A structure with substrates has long been hindered by the difficulty in producing a stable enzyme-substrate complex. "To overcome this challenge, we successfully developed a ...

A new method has enabled the natural structure of particularly large and complex enzymes to be revealed. Scientists at Martin Luther University Halle-Wittenberg (MLU) and TU Berlin have published ...